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FAUC 1104
CAS No. 1869983-86-7
FAUC 1104( FAUC1104 | FAUC-1104 )
Catalog No. M12894 CAS No. 1869983-86-7
A potent, biased allosteric agonist of CXCR3 (pEC50=5.22) that activates solely G proteins.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameFAUC 1104
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, biased allosteric agonist of CXCR3 (pEC50=5.22) that activates solely G proteins.
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DescriptionA potent, biased allosteric agonist of CXCR3 (pEC50=5.22) that activates solely G proteins, induces chemotaxis, but fails to induce receptor internalization or β-arrestin 2 recruitment.
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In Vitro——
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In Vivo——
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SynonymsFAUC1104 | FAUC-1104
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PathwayGPCR/G Protein
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TargetChemokine Receptor
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RecptorChemokine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1869983-86-7
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Formula Weight774.959
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Molecular FormulaC46H54N4O7
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Nametert-Butyl {(S)-1-[(2,2-diphenylethyl)amino]-6-[(S)-2-(4-(4-methoxyphenyl)-4-oxobutanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido]-1-oxohexan-2-yl}carbamate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Milanos L, et al. J Med Chem. 2016 Mar 10;59(5):2222-43.
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